New Anthelmintic


B. C. Allison


Pfizer has received clearance and begun marketing a new anthelmintic, Dectomax, for cattle. It is labeled for control of a broad spectrum of internal and external parasites, including 36 stages of adult parasites, L4 larvae and inhibited larvae shown in the spectrum of control chart. Dectomax is labeled for extended activity in the animals' system. It is labeled to provide up to 21 days of protection against Ostertagia ostertagi. This means that it provides grater than 90% efficacy against any infective larvae surviving and becoming an adult if ingested within 21 days of administration.

Dectomax contains a one percent solution of Doramectin as the active ingredient in an oil based carrier. Doramectin induces a rapid nonspastic paralysis in nematodes and parasitic arthropods as the mode of parasite control. The recommended dosage is one mL per 110 pounds of body weight administered subcutaneously or intramuscularly. However, the Beef Quality Assurance guideline recommendation of subcutaneous administration is the preferred route. It is available in 100, 250, and 500 mL multi-dose, rubber capped amber glass bottles that are contained in a clear polycarbonate shield to reduce the possibility of breakage.

Dectomax is cleared for use in all beef cattle (including pregnant cows, bulls and calves) and dairy replacement heifers up to 20 months of age. Cattle must not be slaughtered for human consumption within 35 days of treatment. Calves that are to be processed for veal should not receive treatment. Dectomax is effective on grubs and, like other systemic treatments for grubs should not be used at times when grubs are in vital areas of the body unless the cattle have been previously treated for grubs due to the danger of host parasite reactions.

DECTOMAX SPECTRUM OF CONTROL
Gastrointestinal Roundworms
(adults and fourth-stage larvae)
Ostertagia ostertagi (including inhibited larvae)
O. lyrata
Haemonchus placei
Trichostrongylus axei
T. colubriformis
T. lingispicularis 1
Cooperia oncophora
C. pectinata 1
C. punctata
C. surnabada (syn. mcmasteri)
Bunostomum phlebotomum 1
Strongyloides papillosus 1
Oesophagostomum radiatum
Trichuris spp. 1

Lungworms (adults and fourth-stage larvae)
Dictyocaulus viviparus

Eyeworms (adults)
Thelazia spp.

Grubs (parasitic stages) 2
Hypoderma bovis
H. lineatum

Sucking Lice
Haematopinus eurysternus
Linognathus vituli
Solenopotes capillatus

Mange Mites
Psoroptes bovis
Sarcoptes scabiei

1 adults
2 1st instar larvae and 2nd/3rd instar larvae

Animal Husbandry Newsletter November 1996
Department of Animal Science, North Carolina State University
Published by North Carolina Cooperative Extension Service, North Carolina State University, Raleigh, North Carolina
Distributed in furtherance of the Acts of Congress of May 8 and June 30, 1914. Employment and program opportunities are offered to all people regardless of race, color, national origin, sex, age, or disability. North Carolina State University, North Carolina A&T State University, U.S. Department of Agriculture, and local governments cooperating.
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